Find out which devices fall within the cleared claims for sterility – Check out our interactive guide.

ANMDO study demonstrates efficacy of low-concentration hydrogen peroxide

 The National Association of Hospital Managers in Italy, ANMDO, has released an article on the data supporting technological efficacy of hydrogen peroxide and silver cation-based decontaminating systems, such as Advanced Sterilization Product’s (ASP’s) GLOSAIR™ 400.



The article reviews clinical studies and experimental tests showing that automated area decontamination systems using a broad spectrum, bioactive disinfectant agent, like a combination of hydrogen peroxide and silver cations, diffused as a mist, can be highly effective against the microbiological risk.

The study draws attention to the fact that current literature available on the impact of healthcare-associated infections (HAIs) shows that, in case of contamination by clinically significant pathogens, such as Clostridium difficile, Mycobacterium tuberculosis, non-tubercular microbacteria (NTM) and Methicillin-resistant Staphylococcus aureus (MRSA), traditional methods of manual cleaning mostly used in hospitals and health care facilities might not be adequate to ensure effective environmental decontamination. This largely due to the many inconsistencies in the application of manual cleaning.

The hydrogen peroxide mist process in ASP’s GLOSAIR™ 400 System, generates minuscule, airborne, electrically-charged particles (8-12µ on average), allowing the mist to work around the hard to reach corners and surfaces of equipment and other obstructions.

The study illustrated that aside from the therapy outcomes of automated hydrogen peroxide and silver cation-based decontaminating systems, there is also a significant cost reduction, improved productivity and assurance of the safety of services provided by hospitals and healthcare facilities.

The study concluded that Automated Area Decontamination is today an effective, method to tackle most pathogens involved in healthcare-related infections and that Published studies show that hospital areas decontaminated through a hydrogen peroxide based system enjoy a reduction and, in many cases, complete eradication of mycobacteria and pathogenic spores, such as C. difficile and MRSA, two of the most common bacteria in hospitals.

The ANMDO society also initiated trials at the University Hospital of Catania and the Clinical Institute of Alessandria, with the aim to verify that the GLOSAIR™ technology is effective in reducing environmental microbial load, verify the effectiveness against specific pathogens that may be present on surfaces and equipment in a hospital environment, and to test how to use the technology, in order to incorporate it with the protocols for cleaning and decontamination.

The trials showed that decontaminating hospital environments using a mist generating device is able to contribute, together with the traditional manual cleaning procedures, in minimizing the microbial load present on the surfaces and on a standard use, minimize also the risk of infections or contamination. From the results obtained it is clear that the area decontamination system with mist combined of hydrogen peroxide (5-6%) and the cations of silver, is particularly effective in performing preventive action when used on a scheduled periodic base additional to the traditional cleaning methods commonly in use in the hospital environment aimed in preventing nosocomial infections and is also able to carry out a treating action in cases of contamination by multiresistant microorganisms that in some cases can cause epidemic clusters.

A decontamination system based on 5-6% hydrogen peroxide and 50 ppm silver cations offers the advantage of a completely automated system as well as the possibility of using a highly effective disinfectant against the microbiological burden with no harm for either humans or the environment. The 5-6% concentration of hydrogen peroxide is considerably lower than some other automated decontamination systems, where it can reach up to 35% in some cases. The use of such a low concentration of hydrogen peroxide ensures safety for operators who start up the machine and avoids altering materials and components that come in contact with the mist; last but not least, normal activities can be quickly resumed in the decontaminated area once aeration of the environment has dropped hydrogen peroxide to acceptable safety levels. If a higher concentration of hydrogen peroxide is used, increased precautions must be observed as there is a higher risk of toxicity for operators and staff, corrosion of exposed materials may occur and longer times of aeration are needed before treated areas can be accessed again.

Please click here to read the full study:

Hospital decontamination: current knowledge of the efficacy of mist-generated (5-6%) hydrogen peroxide and silver cations


Confirmation link

This link will take you to a Web site to which this Privacy Policy does not apply.

We encourage you to read the Privacy Policy of every Web site you visit.